Passa alle informazioni sul prodotto
Smooths fine lines & wrinkles

Smooths fine lines & wrinkles

Brings back youthful radiance

Brings back youthful radiance

Boost elasticity & firmness

Boost elasticity & firmness

Safe and painless to use at home

Safe and painless to use at home

 Excellent 4.8 | 1,465 Reviews

PDRN Advanced Infusion Treatment

PDRN Advanced Infusion Treatment

 

Visibly smooth fine lines, lift sagging skin, and restore youthful firmness in just 5 minutes, twice a month.

Delivers PDRN deep for collagen production

Gentle & safe for sensitive skin

Clinic-level results, zero downtime

See the difference after your first treatment

Ships By: Oct 26
shipping icon FREE Shipping

Safe • Painless • Gentle for sensitive skin

Risk-Free 90-Day Guarantee

That's how confident we are in your results. But if you're not thrilled, send it back and we'll refund your purchase.

What is PDRN?

PDRN (Polydeoxyribonucleotide) is a powerful skin-repairing compound derived from salmon DNA.

With proven regenerative and anti-inflammatory properties, it has been widely used in Korean aesthetic clinics for years, primarily to accelerate healing, restore skin structure, and provide advanced skin rejuvenation treatments.

PDRN is known for its ability to:

  • Stimulate fibroblasts (the cells that produce collagen)
  • Improve tissue regeneration
  • Calm inflammation
  • Accelerate healing from within

We are proud to be one of the first to make this clinically-proven ingredient available as an at-home micro-infusion treatment, so you can get the benefits without the clinic hassle.

Ingredients

Our formula is focused on repair, regeneration, and hydration. Here are the key ingredients that make the difference:

  • PDRN (Salmon DNA): Stimulates skin regeneration and collagen synthesis
  • Niacinamide: Improves tone, texture, and barrier function
  • Panthenol: Soothes, hydrates and supports repair
  • Hyaluronic Acid: Deep hydration that plumps and smooths
  • Centella Asiatica Complex: Calms inflammation and boosts healing

Note: Due to the natural properties of the formula, serum color may vary slightly or fade over time. This does not affect its safety or effectiveness.

All ingredients: Water, Glycerin, Butylene Glycol, Trehalose, Panthenol, Niacinamide, 1,2-Hexanediol, Hydroxyacetophenone, Cyclodextrin, Sodium DNA (Salmon DNA), Carbomer, Gentiana Scabra Root Extract, Sodium Hyaluronate, Arginine, Centella Asiatica Extract, Gardenia Florida Flower Extract, Phellodendron Amurense Bark Extract, Caprylyl Glycol, Mannitol, Madecassoside, Centella Asiatica Leaf Extract, Adenium Obesum Leaf Cell Extract, Asiaticoside, Soluble Collagen

How often should I use it?

Just 5 minutes twice a month. Each treatment uses 1 vial and 1 sterile needle head.

Every order comes with a step-by-step video guide and instructions.

Is it painless and easy to use?

Yes! Our 0.5mm gold-tipped stamp is almost painless and designed for minimal sensation and comfort. The process is simple, takes just 5 minutes and comes with a step-by-step video guide and instructions.

Our formula is gentle on even sensitive skin.

Every order comes with a step-by-step video guide and instructions.

What makes this different from other treatments?

Most anti-aging solutions either sit on the surface (like creams and serums) or require aggressive, costly procedures (like lasers, botox or radiofrequency).

Derm’s Micro-Infusion System combines the precision of our patented gold-plated stamp with a potent collagen-boosting serum—delivering ingredients exactly where they’re needed to address fine lines, wrinkles, and loss of firmness. The result? Clinic-level rejuvenation without pain, downtime, or over-treatment.

How does the Micro-Infusion System work?

Our ultra-thin, painless, gold-plated microneedles create microscopic channels in the skin’s surface. This allows our PDRN-powered serum to penetrate into the deeper layers—where collagen loss, wrinkles, and sagging begin.

Unlike topical creams that work only at the surface, micro-infusion works from within, triggering the skin’s natural repair response for firmer, smoother, more youthful-looking skin over time.

What's included?

Each Micro-Infusion Kit is designed to provide a specific number of treatments. All sterile needle heads are single-use and should be safely discarded after each session to ensure hygiene and optimal results.

Here’s what’s inside:

  • 1-Month Supply → 2 sterile heads + 2 serum vials (2 treatments)
  • 2-Month Supply → 4 sterile heads + 4 serum vials (4 treatments)
  • 3-Month Supply → 6 sterile heads + 6 serum vials (6 treatments)

Each vial and needle head is intended for a single treatment every 2 weeks and should not be reused.

P.S. Every order includes access to a step-by-step video guide to ensure perfect application.

Shipping & Delivery

We process orders within 1-2 business days from our warehouses in the US, Europe, and Asia. Shipments come from the closest warehouse, with delivery times of 4-10 days.

A tracking number will be emailed upon dispatch for easy tracking on our website.

For a limited time, enjoy free shipping on all orders.

90 Day Money-Back Guarantee

We stand 100% by our PDRN Micro-Infusion System. If you don’t see visible improvements in your skin within 90 days, we’ll refund your order.

For returns, please email us at support@try-derm.com

Visualizza dettagli completi
  • Fragrance-Free

  • Alcohol-Free

  • No Artificial Colorants

  • Dermatologically Tested

  • Non-Comedogenic

  • Cruelty-Free

    Real Derm Customer

    Transformations

    ★★★★★

    Derm is rated “Excellent” based on 1,400+ reviews

    Wrinkles & Elasticity

    Wrinkles & Elasticity

    Susan R, 70

    Check #2.svg__PID:b9310597-0787-452f-94d1-38f23272896e

    Verified Customer

    ★★★★★
    • Smooths wrinkles & fine lines
    • Restores skin elasticity & firmness
    • Deeply hydrates & plumps
    Sagging Skin & Neck Wrinkles

    Sagging Skin & Neck Wrinkles

    Regan R, 60

    Check #2.svg__PID:b9310597-0787-452f-94d1-38f23272896e

    Verified Customer

    ★★★★★
    • Firms & lifts sagging skin
    • Reduces neck wrinkles
    • Neck & jaw appear more youthful, firmer and smoother
    Fine Lines & Skin Firmness

    Fine Lines & Skin Firmness

    Barbara D, 62

    Check #2.svg__PID:b9310597-0787-452f-94d1-38f23272896e

    Verified Customer

    ★★★★★
    • Reduces smile lines & smoker lines
    • Supports the skin barrier for firmer skin
    • Boosts collagen for smoother texture
    Hydration & Youthful Glow

    Hydration & Youthful Glow

    Melanie G, 52

    Check #2.svg__PID:b9310597-0787-452f-94d1-38f23272896e

    Verified Customer

    ★★★★★
    • Visibly smooths fine lines
    • Hydrates & plumps for a youthful look
    • Brightens & refreshes tired skin

    Derm's PDRN Micro-Infusion Goes Where Your Anti-Aging Products Can't

    Our patented 24K Gold Micro-Infusion Stamp creates microscopic channels, allowing our potent PDRN (Salmon DNA) serum to reach deeper skin layers where wrinkles form and firmness is lost.

    Inside, this regenerative formula stimulates fibroblast activity and cell renewal — boosting collagen and elastin production to smooth fine lines, lift sagging skin, and restore youthful elasticity from within, all without pain or trauma.

    94%

    saw visible improvement in the appearance of fine lines & wrinkles

    91%

    noticed visibly firmer, more lifted skin after few treatments

    96%

    said their skin felt healthier, more
    hydrated, and rejuvenated

    The Innovative Formula That Sets Us Apart

    +
    HERO INGREDIENT

    PDRN (Salmon DNA)

    A skin-regenerating molecule that stimulates collagen and elastin production.

    +

    Niacinamide

    A multitasking vitamin that brightens uneven tone, refines texture, and strengthens the skin barrier for a healthier, more radiant complexion.

    +

    Panthenol (Pro-Vitamin B5)

    A soothing active that calms, nourishes, and helps skin maintain softness and resilience — ideal for mature or sensitive skin.

    +

    Hyaluronic acid

    A powerful hydrator that plumps skin with moisture, softens the look of wrinkles, and supports elasticity and bounce.

    Formula Image

    4 Simple Steps Firmer, Smoother, Younger-Looking Skin

    Just 5 minutes every 2 weeks.

    Every order comes with a step-by-step video guide and instructions.

    1

    Prep Your Skin

    Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.

    2

    Attach & Prime

    Twist the serum vial directly onto the microneedle head. Hold the device upside down for ~2 minutes to allow full serum flow into the needles.

    3

    Stamp & Infuse

    Gently press the device onto your skin, starting from the center of the face and moving outward with 50% overlap. Focus 2–3 passes over areas prone to fine lines, wrinkles, or loss of firmness.

    4

    Let It Absorb

    Cleanse your face and pat dry. Make sure your skin is clean and ready to absorb.

    One Device, Full-Face Transformation

    We’ve combined two advanced technologies to deliver a complete, at-home solution for fine lines, wrinkles, and loss of firmness.

    One Device,
    =

    All so that you achieve

    Smoother, more youthful skin texture

    Smoother, more youthful skin texture

    Smoother, more youthful skin texture

    Derm vs. Other Solutions.

    See The Difference.

    Feel The Results.

    Aggressive Clinical Treats Basic At-Home Microneedling Topical Creams/Serums
    Targets Fine Lines, Wrinkles & Loss of Firmness at the Source
    Clinic-Level Results from Home
    No Pain or Extreme Discomfort
    Zero Downtime (No Hiding)
    No Risk of Skin Damage
    Long-Lasting, Genuine Skin Regeneration 
    Safe for Mature & Sensitive Skin
    Affordable Professional-Grade Solution 

    Without the Pain or the Price Tag

    • True Skin Rejuvenation

      Our system delivers PDRN deep into the skin’s renewal layers, boosting collagen and elastin where fine lines and sagging begin.

    • No Clinic. No Downtime.

      Skip invasive procedures and recovery time. Enjoy a 5-minute at-home ritual with real results and zero life on hold.

    • Lasting Results. No Illusion.

      Tired of temporary fixes? Our system triggers true collagen renewal for improvements that last.

    • Gentle on Sensitive Skin

      Soothes as it works, supports your skin barrier, and hydrates deeply, without irritation. Designed for even the most delicate skin.

    • Smart Investment. Real Payoff.

      Why spend thousands at the clinic? Get professional-grade rejuvenation for a fraction of the cost. Your confidence is worth it.

      Formulated By Experts,
      Recommended By Dermatologists

      Right now, there is nothing on the market that even comes close to the anti-aging results that the dermalux Micro Infusion System delivers, nor is there anything with as much scientific evidence supporting its effectiveness!

      Guarantee Badge

      See Results In 90 Days Or Your Money Back

      We believe you’ll love the transformation and we’re willing to prove it.

      That’s why this time, we’re making it simple:
      Try our PDRN Micro-infusion System for 90 days and if you don’t see visible results, we’ll give you a full refund.

      No questions asked.

      Get Better Skin Today

      Real Skin. Real Change.

      Traci G.

      Visible Improvement

      Redness & Rosacea

      I’ve struggled with mild rosacea for years, and most anti-aging products only made it worse. After just a few treatments, the redness is noticeably reduced, and the fine lines around my eyes and mouth are much softer."

      Traci G. Verified Customer

      ⭐⭐⭐⭐⭐ - from United States
      Purchased: 6 Month Supply
      Theresa R.

      Visible Improvement

      Smoothed Fine Lines

      “I started noticing fine lines in my late 30s, and nothing I tried made a real difference. After four treatments, those lines are so much softer and my skin looks smoother, brighter, and more refreshed. Even my friends have commented that I look more rested!"

      Theresa R. Verified Customer

      ⭐⭐⭐⭐⭐ - from United States
      Purchased: 3 Month Supply
      Lucille B.

      Visible Improvement

      More Even Tone

      “I used to have uneven skin with dullness that no makeup could fully cover. After some treatments, my complexion looks brighter, smoother, and so much more even. The discoloration have faded, and my skin just looks healthier overall. I feel confident without foundation for the first time in years!”

      Lucille B. Verified Customer

      ⭐⭐⭐⭐⭐ - from United States
      Purchased: 6 Month Supply

      Professional Results Without the Professional Price

      Feeling good in your skin shouldn’t cost thousands

      You could spend each year:

      $3,000+ on injectables

      $1,800+ on repeat medi-spa visits

      $1,100+ traditional skincare


      Or, get 6 full treatments and start seeing change from home — for a fraction of the cost of a single clinic session.

      Still Got Questions?

      Many users notice smoother, more hydrated skin after just one treatment — often describing a fresh glow and softer texture within 24–48 hours. That’s because the micro-infusion process immediately boosts hydration and wakes up your skin’s repair response.

      However, for visible, lasting improvement, we recommend completing at least 6 treatments over 3 months.

      Regular use may help support a firmer, more radiant look over time.

      Consistency matters more than speed — and we’re here to support you through that journey.

      It combines precision micro-infusion with a clinically proven collagen-boosting serum powered by PDRN.

      The ultra-fine, painless 24K gold needles create micro-channels in your skin, allowing the serum to reach the deeper layers where collagen loss and structural changes cause wrinkles and sagging.

      This process stimulates new collagen and elastin production, helping to lift, firm, and smooth the skin from within — for a more youthful, resilient complexion over time.

      Each Micro Infusion System includes single-use sterile microneedle heads and serum vials.

      1-Month Supply → 2 treatments (2 needle heads and 2 serum vials)
      2-Month Supply → 4 treatments (4 needle heads and 4 serum vials)
      3-Month Supply → 6 treatments (6 needle heads and 4 serum vials)

      We recommend one session every 2 weeks to give your skin time to regenerate properly. This rhythm supports long-term collagen activation and minimizes irritation.

      After each session, it is recommended to dispose of the used needle head and apply any remaining serum on your skin.

      Each order comes with an easy to follow step-by-step video guideline.

      The device uses ultra-fine, sterile 24K gold microneedles designed to gently penetrate only the uppermost layer of skin.

      While they are long enough to trigger collagen and increase serum absorption, they are also thinner than a human hair, which makes the treatment very tolerable — even for beginners.

      You might feel a light tingling or pricking during application, especially in more sensitive areas. But there’s no dragging, tearing, or numbing required.

      Most people describe it as a gentle tapping sensation — and get used to it within seconds.

      Derm’s micro-infusion system uses microneedles that are 0.5mm in length — ideal for what's called “epidermal needling.”

      This depth allows the serum to reach the upper dermis — the layer where fine lines begin and skin firmness starts to decline — without causing pain or requiring medical supervision.

      It’s long enough to:
      - Stimulate collagen and elastin production
      - Boost skin cell renewal for smoother texture
      - Enhance absorption of active ingredients up to 30× more effectively than topical application

      At the same time, it's short enough to avoid bleeding or downtime, making it perfectly safe for at-home use — even for beginners.

      Yes. Our formula and delivery system are both designed to be non-comedogenic, non-irritating, and safe for all skin types and tones.

      We don’t use harsh acids, retinoids or bleaching agents. If your skin is extremely reactive, we recommend a patch test first, or consulting a dermatologist.

      Yes — while it’s designed to target fine lines, wrinkles, and loss of firmness, the same technology can help improve the appearance of acne scars.

      Our ultra-fine, painless 24K gold needles create micro-channels in the skin, allowing the PDRN-powered serum to reach the deeper layers where both aging and scar texture originate.

      This stimulates collagen production, refines texture, and can visibly reduce the look of shallow scars over time.

      We recommend waiting until active breakouts have calmed before using the device.

      Using microneedles on inflamed or broken skin may lead to irritation or delayed healing.

      Yes — it can be safely used on the neck, lips, and most areas of the body where you want to improve skin texture, smooth fine lines, or boost firmness.

      Many users apply it also to areas with:
      - Crepey skin on the décolleté
      - Fine lines and loss of firmness along the neck and jawline
      - Textural irregularities or dryness on the arms or hands

      For sensitive zones like lips and neck, apply with light pressure and follow our guided stamping technique.

      However, avoid using the device directly on the eyelids or waterline. We recommend keeping at least 1.5 inches (around 3 cm) away from the eyes to protect delicate skin.

      Every order includes a detailed step-by-step video guide to show you exactly how and where to apply it for best results.

      After each treatment, your skin is in “recovery mode” — and also more receptive to anything you apply. To protect your results and avoid irritation, we recommend the following:

      First 24 hours:

      - Avoid makeup, sun exposure, and sweating (no gym, sauna or steam)
      - Do not apply active ingredients like retinol, acids, scrubs, or exfoliants
      - Keep skin clean and hydrated using a gentle, fragrance-free moisturizer
      - Try not to touch your face, especially with unwashed hands

      Day after:

      - Wash your face with a mild cleanser, pat dry, and moisturize
      - If you go outside, apply a high-quality, non-comedogenic SPF

      What’s normal:

      It’s common to experience light redness, dryness or a tight feeling for a few hours. Some users may notice slight flaking or peeling a few days later — a sign your skin is renewing.

      Pro tip:

      Your skin absorbs ingredients up to 3x better after infusion, so avoid applying anything harsh during this window. Stick to calming, barrier-repair formulas only.

      Most users return to their full skincare routine within 48 hours — but you may not even feel the need for much. The serum does most of the work.

      Yes — but with a few important guidelines. Right after your treatment, your skin is more permeable and sensitive. This means ingredients absorb better, but it also makes your skin more reactive.

      Here’s what you can use:

      - Hyaluronic acid or hydrating moisturizers: apply in the evening after treatment to boost hydration and support healing
      - Fragrance-free, calming creams (e.g., with panthenol, ceramides, or Centella) are also recommended

      Here’s what to avoid for 24–48 hours:

      - Retinol (Vitamin A)
      - Exfoliating acids (glycolic, lactic, salicylic)
      - Vitamin C serums, scrubs, or strong actives
      - Any skincare with fragrance or alcohol

      It’s simple and takes just a few minutes. Whether you're new to skincare or an experienced user, you’ll find the process easy to follow — and incredibly rewarding. Here’s how it works:

      1. Prep Your Skin

      Start with a freshly cleansed face. Gently pat dry and ensure your skin is free of any products.

      2. Attach & Prime

      Twist the serum vial directly onto the microneedle head. Then hold the device upside down for about 2 minutes, allowing the serum to fully saturate the needles.

      3. Stamp & Infuse

      Gently press the device onto your skin, beginning at the center of the face and working outward. Use a 50% overlap between stamps, and repeat 2–3 passes over areas prone to fine lines, wrinkles, or loss of firmness. Avoid stamping directly over active breakouts.

      4. Let It Absorb

      Pat any leftover serum onto your face and neck. Leave the serum on overnight, and avoid makeup or sun exposure for the next 24 hours.

      The entire treatment takes 5–10 minutes. Every order includes a step-by-step video guide to help you use it with confidence — even if it’s your first time.

      We don’t recommend using third-party serums. The DERM formula was developed to work with micro-infusion: it’s lightweight, fast-absorbing, and enriched with actives like PDRN, Niacinamide, and Panthenol.

      Other serums may contain irritants or molecules too large to penetrate through micro-channels — wasting your treatment or even causing sensitivity.

      Once you’ve reached your desired results, you don’t need to use it as often — many switch to a maintenance rhythm, like once a month.

      The results typically last several weeks, depending on your skin type, age, and skincare routine. Regular use helps prolong and maintain the effect over time.

      Rollers create micro-injuries — but don’t deliver ingredients into the skin.

      Our Micro Infusion System not only creates the micro-channels, it also infuses a clinically active serum directly where aging forms.

      Plus:

      - It uses sterile, single-use heads
      - Rollers often get reused, increasing risk of irritation & bacteria
      - Our stamping mechanism is more precise, less damaging

      Yes, but we suggest waiting at least:
      - 2 weeks after fillers / Botox
      - 4/6 weeks after laser treatments

      And as always — check with your dermatologist if you're under clinical care.

      No extensive prep needed. Just clean your face thoroughly, make sure your hands are clean, and you're good to go.

      Optionally, apply a gentle toner or hydrating mist before starting to help serum spread evenly.

      Absolutely not. Signs of aging affect everyone — and this treatment is designed to work for all genders and all skin types.

      We see incredible results with men who want to smooth fine lines, improve skin texture and regain confidence without a 10-step routine or clinic visits.

      Our money-back guarantee ensures that if you are not satisfied with your purchase, you can return the item within 90 days of receipt for a full refund.

      Simply contact our customer service team to initiate the return process, and follow the provided instructions.

      Once we receive the returned item, we will process your refund within 5-7 business days.

      For returns, please email us at support@try-derm.com

      Read Real Reviews From Our Customers

      4.8
      Based on 1,465 reviews
      1147
      271
      28
      6
      13
      Linda

      Linda

      Verified Buyer

      United States

      Fine lines are softer finally

      I’ve been trying to get ahead of the lines forming around my eyes and mouth for a while. Most things either do nothing or just irritate my skin. This is the first treatment that actually made a visible difference. The fine lines look softer, especially when I smile, and my skin feels a little firmer overall. I’m honestly impressed.

      Samantha

      Samantha

      Verified Buyer

      United States

      Feels like my skin is holding itself up better

      I started noticing a bit of sagging around my jaw (I'm 56). Didn’t want to jump into fillers yet, so I gave this a shot. It’s been two months and my face just looks… lifted? Not in a dramatic way just firmer, healthier and more "together." It’s a good feeling

      Sylvia

      Sylvia

      Verified Buyer

      United States

      THE REAL AMAZING PRODUCT

      I have tried every product out there, and this is the one that works after spending thousands of dollars on products that promised results and did nothing. I recently went for my yearly body scan, and my dermatologist said You look amazing. What are you doing? I told her about micro infusion and Derm skin care, the pdrn serum! Well, you now have a new client. Can't say enough about this product:)

      Mary

      Mary

      Verified Buyer

      United States

      Love!

      I just love this pdrn infusion serum...it's amazing. My wrinkles are alot less noticeable(marionette lines).

      Susanne

      Susanne

      Verified Buyer

      United States

      Worth the wait

      I didn’t notice much until the 2th treatment. Then suddenly… my skin just looked smoother and more lifted. The lines around my mouth were softer, and my overall tone looked brighter. It’s not an overnight miracle, but if you stick with it, it really delivers.

      Kristin

      Kristin

      Verified Buyer

      United States

      Didn’t realize how dry I was until this

      I thought my routine was solid, but apparently I was just layering product on top of thirsty skin. This made everything absorb better and honestly changed how my face feels. It’s softer, less tight, and my forehead lines don’t crease as much during the day...

      Jack

      Jack

      Verified Buyer

      United States

      Love it so far

      I’m not into skincare. I hate long routines. But this is quick, painless, and after each treatment my skin just feels better. Like it's doing something under the surface. Less oily, more balanced. Even my barber asked what I’m using. That never happens.

      Karen

      Karen

      Verified Buyer

      United States

      Skin finally looks awake again

      I wasn’t dealing with scars or anything like that, I just felt like my skin looked… tired. Like it lost its glow completely. I wasn’t expecting much, but after a few treatments, something changed. It’s hard to explain, it just looks more alive now and fresher. People have commented on it too, which never happens.